Back in early December, a little boy in southern Guinea caught a mysterious disease. He had a fever, was vomiting and had blood in his stool.

The boy died a few days later. Before he did, he passed the disease to his 3-year-old sister, his mother, his grandmother and a midwife. The latter was eventually hospitalized in Gueckedou, a nearby city of 200,000 people.

By March, the disease spread to four cities. And international health officials realized they had an Ebola outbreak on their hands.


[MICHAELEEN DOUCLEFF: "Could A 2-Year-Old Boy Be 'Patient Zero' For The Ebola Outbreak?" (2014/08/25) on NPR]
2014年3月23日にはWHOのリリースが出て、4月16日付で、ここまでの追跡結果が論文発表されている。しかし、この2歳の少年は発端患者ではなく、それより前の感染者は不明だという。現地から米国に戻ったばかりのCDCの感染症専門医のPierre Rollinによれば...
Rollin thinks these two kids were likely early cases of the outbreak but not the first cases. "Lots of people are talking about patient zero," Rollin says. "It's not patient zero. It's [that] the chain stopped there [at the boy] because we cannot find anybody else or nobody can remember anything."


To find the origin of the outbreak, a team with Doctors Without Borders went to Gueckedou and interviewed people whose relatives had died of what looked like Ebola. "So it was a virtual chain," Rollin says. None of the cases were confirmed in the lab. And by the time researchers reached people, many had a hard time remembering what had happened months ago.


[MICHAELEEN DOUCLEFF: "Could A 2-Year-Old Boy Be 'Patient Zero' For The Ebola Outbreak?" (2014/08/25) on NPR]

posted by Kumicit at 2014/08/28 08:47 | Comment(0) | TrackBack(0) | Disease | このブログの読者になる | 更新情報をチェックする


コンゴ民主共和国(人口7743万人, GDP $400/人)(DR Congo, 旧ザイール)でのアウトブレイクは、WHOの発表によれば、最初に野生動物から感染した人が死亡したのは2014年8月11日で、接触者80名がフォローアップされている。
The index case was a pregnant woman from Ikanamongo Village who butchered a bush animal that had been killed and given to her by her husband. She became ill with symptoms of EVD and reported to a private clinic in Isaka Village. On 11 August 2014, she died of a then-unidentified haemorrhagic fever. Local customs and rituals associated with death meant that several health-care workers were exposed and presented with similar symptoms in the following week.

Between 28 July and 18 August 2014, a total of 24 suspected cases of haemorrhagic fever, including 13 deaths, have been identified. Human-to-human transmission has been established and includes the health-care personnel who were exposed to the deceased pregnant woman during surgery (one doctor and two nurses) in addition to the hygienist and a ward boy, all of whom developed symptoms and died. Other deaths have been recorded among the relatives who attended the index case, individuals who were in contact with the clinic staff, and those who handled the bodies of the deceased during funerals. The other 11 cases are currently being treated in isolation centres.

Samples have been sent to laboratories in Kinshasa and in Gabon for confirmation of EVD and to identify the strain. The index case and the 80 contacts have no history of travel to the EVD-affected countries in West Africa (Guinea, Liberia, Nigeria, or Sierra Leone) or history of contact with individuals from the affected areas. At this time, it is believed that the outbreak in DRC is unrelated to the ongoing outbreak in west Africa.




[WHO 2014/08/27]

posted by Kumicit at 2014/08/28 08:07 | Comment(0) | TrackBack(0) | Disease | このブログの読者になる | 更新情報をチェックする